Matthew's at San Marco 
2107 Hendricks Avenue
Jacksonville, FL 32207
904-396-9922

A creative blend of Southern, Mediterranean, Asian, regional American, and Middle Eastern dishes are on the menu at this restaurant that also features a wine list with over 420 selections available. A five course tasting menu is also available that changes nightly and reservations are recommended. They are open Monday through Saturday for dinner only; closed on Sundays.