Mother-In-Law House Restaurant 500 South Main Street, St. Charles, MO 63301, 636-946-9444, Known for their Coconut Cream Pie, this restaurant serves a full menu of American cuisine including homemade soups and daily specials. They are closed on Sunday. more... 

Bob Evans Restaurant 1998 Zumbehi Road, St. Charles, MO 63303, 636-949-0900, Family restaurant that serves a full American menu daily for breakfast, lunch, and dinner. Breakfast is available all day. 

Lewis & Clark's American Restaurant 217 South Main Street, St. Charles, MO 63301, 636-947-3334, Located in a turn-of-the-century, three story building, this restaurant serves delicious American cuisine and features a patio that overlooks Main Street. They are open daily for lunch, dinner, and late night dining. more... 

Maryland Yards at the Water Works 1200 South Main Street, St. Charles, MO 63301, 636-757-9273, Located in the old Water Works Building on Main Street, the fare is American with the largest deck in St. Charles. Prices are very reasonable and the atmosphere is one-of-a-kind. more...

Miss Aimee B's 837 First Capitol Drive, St. Charles, MO 63301, 636-946-4202, Located in a 1865 historical house, this charming restaurant serves homemade American cuisine and delicious desserts Monday through Saturday for breakfast and lunch. They are closed on Sunday. more... 

Tony's on Main Street 132 North Main Street, St. Charles, MO 63301, 636-940-1960, Enjoy unique American cuisine at this restaurant with entrees including hand cut steaks, chicken nachos, garlic shrimp, and homemade desserts. They are closed every Monday, open Tuesday-Thursday from 11am-9:30pm, Friday from 11am-10:30pm, Saturday from 3pm-10:30pm and Sunday from 4pm-8:30pm. They also offer lunch buffet Tuesday-Friday from 11am-1:30pm.  more... 

Vivian's Vineyards 1409 North Second Street, St. Charles, MO 63301, 636-940-8444, Known as having the second best margarita in the world, this elegant restaurant serves delicious American fare Monday through Saturday for dinner only. They are closed on Sunday. more... 

Wiliker's 1566 Country Club Plaza, St. Charles, MO 63303, 636-947-1441, Specializing in delicious steaks and fresh seafood, this restaurant serves a full American style menu daily for lunch and dinner. more... 

Judd's Memphis Best Bar-B-Que & Grill 2795 Veteran Memorial Parkway, St. Charles, MO 63303, 636-947-8345, Enjoy Memphis style barbecue at this restaurant that is filled with Elvis, Memphis, and blues memorabilia. They also serve steaks, seafood, cocktails, and have a huge beer selection. They are open daily for lunch and dinner. 

Trailhead Brewing Company 921 South Riverside Drive, St. Charles, MO 63301, 636-946-2739, Located in a 200-year-old mill building, this brew pub features handcrafted beer brewed on the premises and serves smoked and grilled American entrees. They are open daily for lunch, dinner, and late night dining. more... 

Magpie Cafe 903 South Main Street, St. Charles, MO 63301, 636-947-3883, Charming cafe that serves homestyle American cuisine including quiche, homemade desserts, and baked potato soup daily for lunch only. more... 

Chong Jing Garden Four Hawks Nest Plaza, St. Charles, MO 63303, 636-946-5980, Specializing in Hunan and Mandarin cuisine, this Chinese restaurant serves a wonderful menu of Chinese specials Monday through Saturday for lunch and dinner. They are closed on Sunday. 

Winery of the Little Hills 501 South Main Street, St. Charles, MO 63301, 636-946-9339, Featuring a beautiful outdoor wine garden, this restaurant offers outstanding French and American cuisine complemented by premium Missouri wines. They are open Monday through Saturday for lunch and dinner; closed on Sunday. more... 

St. Charles Vintage House Restaurant 1219 South Main Street, St. Charles, MO 63301, 636-946-7155, A German and American gourmet menu is served at this family style restaurant that offers a buffet and special menus by arrangements. They are closed on Monday. 

Fratelli's Restaurant 2061 Zumbehl Road, St. Charles, MO 63303, 636-949-9005, Authentic Italian cuisine created from old family recipes is the specialty at this restaurant with entrees including pastas, veal, pizza, steaks, and chicken. They are open Monday through Friday for lunch and dinner and open on Saturday and Sunday for dinner only. 

Pio's Restaurant 401-403 First Capitol Drive, St. Charles, MO 63301, 636-724-5919, Family owned restaurant that serves a full Italian and American style menu with many of the entrees created from homemade recipes. They are open daily for lunch and dinner. 

Chevy's 2911 Veterans Memorial Parkway, St. Charles, MO 63303, 636-946-3434, Fresh Mexican cuisine is the specialty at this restaurant with all items on the menu made-from-scratch. They are open daily for lunch and dinner. 

Hotshots Sports Bar & Grill 1636 Country Club Plaza Drive, St. Charles, MO 63303, 636-947-8833, Open daily for lunch, dinner, and late night dining, this sports bar features big screen TV's playing your favorite sports, pool tables, darts, and interactive trivia. A variety of American, Italian, and homestyle cuisine is served. 

Krieger's Pub and Grill 2893 Veterans Memorial Parkway, St. Charles, MO 63303, 636-947-1445, Over 20 TV's that broadcast five to seven different games at any time are featured at this restaurant, that serves great pub style food. They are closed on Sunday. 

Rumples Pub 221 North Main Street, St. Charles, MO 63301, 636-949-7678, Beautiful and relaxing pub that is filled with antiques and serves steaks, seafood, chicken, and pasta dishes by candlelight. They are closed on Mondays. 

Steakhouse, The 1260 South Main Street, St. Charles, MO 63301, 636-949-7777, Elegant restaurant that features the finest cuts of beef, as well as, fresh seafood and savory chicken entrees, all served in a casual and comfortable atmosphere. They are open for dinner only and closed on Monday.