Applebee's Neighborhood Grill 820 North Bridge Street, Chillicothe, OH 45601, 740-702-7753, American cuisine served in a casual atmosphere. Types of food served include sandwiches, seafood, and steaks.

Cardo's Restaurant & Bar 27 West Second Street, Chillicothe, OH 45601, 740-775-2564, This casual restaurant is a popular hangout, featuring pool tables, televisions, dart boards, foosball tables, karaoke and live entertainment. Cardo's menu, available for pick-up, dine-in or delivery; includes specialty pizzas, subs, salads and more. more...

Max & Erma's Restaurant 10 River Trace Drive, Chillicothe, OH 45601, 740-773-2323, Max & Erma's is a popular family restaurant that serves food that is prepared using the freshest, highest quality ingredients available. Menu selections include gourmet hamburgers, tortilla soup, fried shrimp, chicken salad croissant, tomato mozzarella chicken sandwich, petit filet mignon, caramel fudge cheesecake, steamed vegetables, and fresh-baked cookies.  more...

Old Canal Smoke House 94 East Water Street, Chillicothe, OH 45601, 740-779-3278, Open Monday through Saturday, this local favorite offers lunch and dinner options ranging from smoked prime rib to savory side dishes. Patio dining is available.

Sumburger Restaurant 1487 North Bridge Street, Chillicothe, OH 45601, Located Near Shopping Centers, 740-772-1055, One of the few original 1950's drive-ins left today, this unique eatery serves fish or chicken dinners, hamburgers, sandwiches, a variety of sides, ice cream sundaes and more. Drive-in and order from your car, or eat inside, using the phone at the table to place your order.  more... 

Joy O' Java 1075 North Bridge Street, Suite 110, Chillicothe, OH 45601, Located in the Chillicothe Mall, 740-779-9090, Joy O' Java, a popular locally owned and operated coffee shop, specializes in specialty coffees, blended teas, and other custom drinks. Soft drinks and fresh-baked pastries are also available. Joy O' Java is equipped for wireless Internet.  more...

Casa del Taco 1055 North Bridge Street, Chillicothe, OH 45601, 740-773-7650, Patrons are giving rave reviews for Casa del Taco's tasty, fast food-style Mexican entrees, which include a wonderful Mexican chef salad, tacos, and burritos.

Tumbleweed Restaurant 1150 North Bridge Street, Chillicothe, OH 45601, 740-779-6195, Family friendly restaurant offering Tex-Mex cuisine as well as a large menu of mesquite-grilled steaks, chops, chicken and seafood cooked over real mesquite logs on a specially designed grill.

Damon's Grill 10 North Plaza Boulevard, Chillicothe, OH 45601, 740-775-8383, Large screen televisions are located throughout this full service, casual dining restaurant that offers dining in a family atmosphere with a menu that includes their award-winning ribs, grilled steaks, fresh seafood, salads, and chicken dishes.