Located in the heart of downtown, the Rochester Marriott Mayo Clinic Hotel is only 8 miles from the Rochester International Airport (RST) and offers easy access to our most popular attractions through our climate-controlled pedestrian subway and skyway. Visit the world-famous Mayo Clinic. Indulge in shopping at University Square. Or set out for adventure with biking, fly fishing, and horseback riding nearby. Historical tours nearby include Assisi Heights and Mayowood Mansion. Minneapolis-St. Paul is an easy day trip from the Rochester Marriott. Business travelers working with Rochester Methodist Hospital, Relion, Norandex, or other area companies will enjoy the spacious guest rooms with well-lit work desks and high-speed Internet. Host work sessions in the large boardroom of this downtown Rochester Minnesota hotel. Unwind from a busy day in our atrium lobby, or grab a drink at our casual, American-style Oak Room Restaurant. Discover the warm, reassuring comfort of this Marriott hotel in Rochester, Minnesota.