Sikeston, MO,Vacation Rentals By Owner on VRBO® Renting a private vacation home offers the affordability, exceptional value, and personal attention that you deserve. Most private vacation homes offer considerably more space than you will find in the typical hotel room often at a reduced cost. Now, families can vacation together and still have room to breathe. View their list of vacation rentals now...

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Best Western Coach House Inn 220 South Interstate Drive, Sikeston, MO 63801, 573-471-9700, The Best Western Coach House Inn has 63 spacious suites, including standard, deluxe and executive suites. All rooms feature air-conditioning and heat, cable television, alarm clock and radio. Some suites also have a refrigerator.  

Country Hearth Inn 100 Matthews Lane, Sikeston, MO 63801, 573-472-4400, This hotel offers local calls, delicious breakfast and homemade chocolate chip cookies. Rooms available include hot tub suites with microwave and refrigerator. 

Days Inn 1330 South Main Street, Sikeston, MO 63801, 573-471-3930, This property features a complimentary breakfast, freshly baked cookies available in the lobby from 4 PM, free coffee available in lobby 24 hours, an indoor swimming pool, and wireless internet. 

Drury Inn 2602 East Malone, Sikeston, MO 63801, 573-471-4100, Drury Inn serves a hot breakfast and offers high-speed internet access in every room. In addition, to these amenities you can always take advantage of evening beverages and snacks (Mon-Thur 5:30-7:00 pm), iron/ironing board, hairdryers, in-room coffee and much more. This hotel has 80 spacious guestrooms with flexible workspace that appeal to business travelers as well as families.  

Holiday Inn Express 120 South Interstate, Sikeston, MO 63801, 573-481-9500, The Holiday Inn Express Sikeston Hotel is located at Mile Marker 67, off Interstate 55. Hotel features include a continental breakfast, outdoor pool, indoor whirlpool, exercise room and cable with HBO.  

Pear Tree Inn 2602 Rear East Malone, Sikeston, MO 63801, 573-471-8660, This hotel has 67 spacious guestrooms that appeal to families and is equipped for business travelers with flexible workspace. Enjoy a continental breakfast daily and a rate that will fit your travel budget.  

Super 8 Motel 2609 East Malone, Sikeston, MO 63801, 573-471-7944, This convenient location off of Interstate 55 features wireless internet, cable TV and a complimentary breakfast served daily. 

Town & Country RV Resort 298 Highway 62 East, Sikeston, MO 63801, 573-472-1339, 800-771-1339, This landscaped RV park is well-maintained and offers 60 spacious, level sites. Weekly rates are the norm, but monthly rates are available for those guests who just want to stay awhile. more...