Big Pink Guesthouse 312 John Lee Hooker Lane, Clarksdale, MS 38614, Located in the Heart of Blues Alley, 662-645-1815, Big Pink, a mixture of elegant Victorian and funky Big Easy, is a private retreat. The entire first floor, including the kitchen, is dedicated to public space, which guests in both suites can use. The second floor is divided into two private areas, both of which comfortably accommodate two adults. Big Pink is the perfect setting for private parties, weddings, receptions and meetings of all types.

Riverside Hotel 615 Sunflower Avenue, Clarksdale, MS 38614, 662-624-9163, Originally a hospital, The Riverside Hotel was bought in 1944 and turned into a hotel where guests such as John Lee Hooker, Muddy Waters, Ike Turner, Sam Cooke, and John F. Kennedy, Jr. have stayed. A memorial for blues artist Bess Smith, who died in 1937, is located in Room #2 for this was the emergency room where she died when the hospital was open.

Shack Up Inn at Hopson Plantation 001 Commissary Circle, Clarksdale, MS 38614, Four Miles From Crossroads of Highways 61 & 49, 662-624-8329, Tour the virtually unchanged plantation, enjoy live music at the Commissary, and then sleep in one of the renovated shotgun shacks. Tin roofs, antique bathtubs and more await you in this interesting spot.

Clarksdale, MS,Vacation Rentals By Owner on VRBO® Renting a private vacation home offers the affordability, exceptional value, and personal attention that you deserve. Most private vacation homes offer considerably more space than you will find in the typical hotel room often at a reduced cost. Now, families can vacation together and still have room to breathe. View their list of vacation rentals now...

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Rentalo.com Vacation Rentals, Hotels, Bed & Breakfasts, Clarksdale, MS, Save time finding the best deals on vacation properties that meet your needs. Use this FREE inquiry service today! Rentalo.com was featured under [Best of the Web] vacation rentals traveler-tested websites you need to know about by the National Geographic Traveler magazine, with over 120,000 vacation properties in 15,000 destinations worldwide!

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Best Western 710 South State Street, Clarksdale, MS 38614, Located on U.S. Highway 61 South, 662-627-9292, Located in the heart of the Mississippi Delta, the Best Western Executive Inn is the perfect place for both business and leisure travelers stay when in the area. All guest rooms have microwaves, refrigerators, coffee makers, irons and ironing boards, dataports, desks, and in-room movies. Enjoy the continental breakfast, heated indoor/outdoor swimming pool, exercise room, basketball court, and meeting facility. 

Comfort Inn 818 South State Street, Clarksdale, MS 38614, Located on Highway 61, 662-627-5122, Near major Clarksdale restaurants, Ground Zero, Madidi's, Blues Alley, and the Delta Blues Museum, Comfort Inn is an interior corridor lodging establishment. All guest rooms microwaves, refrigerators, coffee makers, hair dryers, irons, ironing boards and cable television. Suites are available. A deluxe continental breakfast and guests will enjoy the use of the swimming pool and exercise facility. 

Royal Inn 1910 State Street, Clarksdale, MS 38614, 662-624-4391, This independent motel has 99 rooms, king-size beds, an outdoor pool, fax and photocopying services, conference and banquet facilities, and serves a continental breakfast.  

Coahoma County Expo Center 1150 Wildcat Drive, Clarksdale, MS 38614, 662-627-7337, This Expo Center and livestock facility is the host of many events, including festivals, concerts, racing events, conventions, and flea markets, each year. There are over 400 RV pads with water and electricity and some with sewer hook-ups.