Florence South Carolina Lodging

Hotels, Lodges, Extended Stay

• Best Western Inn
  1808 West Lucas Street • Florence, SC 29501
  843-678-9292
  A variety of amenities are in all of the 74 tastefully decorated guest rooms at this hotel such as... more...  map

• Comfort Inn
  1916 West Lucas Street • Florence, SC 29501
  843-665-4558
  A variety of spacious guest rooms with an array of great amenities are available at this hotel with... more...  map

• Country Hearth Inn
  831 South Irby Street • Florence, SC 29501
  843-662-9421
  A wide variety of amenities are on site at this elegant hotel including a fitness center, an... more...  map

• Country Inn & Suites
  1739 Mandeville Road • Florence, SC 29501
  843-317-6616
  Hotel features a continental breakfast, local calls, spacious guest rooms feature desk,... more...  map

• Courtyard By Marriott
  2680 Hospitality Boulevard • Florence, SC 29502
  843-662-7066
  Relax in one of the 90 beautifully appointed guest rooms at this hotel with all rooms including... more...  map

• Days Inn
  2111 West Lucas Street • Florence, SC 29501
  843-665-4444
  One king sized bed or two queen sized beds are in all of the 103 spacious guest rooms at this hotel... more...  map

• Days Inn Lake City
  170 South Ron McNair Boulevard • Lake City, SC 29560
  843-394-3269
  Days Inn of Lake City SC is located on Highway 52, accessible from Rt 378 off I-95. They are a family friendly motel in a quite, peaceful area within walking distance to our downtown shops. They have a beautiful outdoor pool, high speed internet access, and a continental breakfast each morning.  map

• Days Inn South
  3783 West Palmetto Street • Florence, SC 29501
  843-665-8550
  There are 120 comfortably appointed guest rooms at this hotel that offers microwaves and refrigerators in some of the rooms upon request and irons and ironing boards at the front desk. A full service restaurant that serves delicious country cuisine is on site, as well as an outdoor swimming pool and Jacuzzi. Golf packages are available and guests receive a pass to a nearby tennis court.  map

• Econo Lodge North
  1811 West Lucas Street • Florence, SC 29501
  843-665-8558
  This hotel offers guests a delicious continental breakfast, ocal calls an indoor heated pool with... more...  map

• Fairfield Inn Florence
  140 Dunbarton Drive • Florence, SC 29501
  843-669-1666
  All of the 135 spacious and comfortable guest rooms at this hotel have work desks with lamps, data... more...  map

• Guesthouse International
  2001 West Lucas Street • Florence, SC 29503
  843-669-1921
  The GuestHouse International Inn is a beautiful property located on 7 acres of spacious, landscaped... more...  map

• Hampton Inn & Suites Florence North I-95
  1735 Stokes Road • Florence, SC 29501
  843-662-7000
  The Hampton Inn & Suites Florence North I-95 is just off I-95 and offers many amenities like a hot... more...  map

• Hampton Inn & Suites Florence-Civic Center
  3000 Radio Drive • Florence, SC 29501
  Adjacent to the Florence Civic Center
  843-629-9900
  Beautiful three story, award-winning hotel that offers standard guest rooms with one king sized bed... more...  map

• Holiday Inn Express Hotel & Suites
  2101 Florence Harlee Boulevard • Florence, SC 29506
  843-629-9779
  This four-story, interior corridor hotel boasts 86 guest rooms & suites. It offers a heated indoor... more...  map

• Holiday Inn Hotel & Suites
  1819 West Lucas Street • Florence, SC 29501
  843-665-4555
  Full service hotel that offers 204 luxuriously appointed guest rooms and suites with all rooms... more...  map

• Howard Johnson Express Inn
  3821 Bancroft Road • Florence, SC 29501
  843-664-9494
  An Award Winning, AAA approved property, this hotel is a perfect stopping point between Florida and... more...  map

• Microtel Inn
  1912 Enterprise Drive • Florence, SC 29502
  843-629-9523
  This property proudly offers a central location near area businesses and attractions. The... more...  map

• Ramada Inn
  2038 West Lucas Street • Florence, SC 29501
  Intersection of Interstate Hwy. 95 & U.S. Hwy. 52
  843-669-4241
  A variety of standard amenities are found in the 179 graciously inviting and spacious guest rooms... more...  map

• Red Roof Inn
  2690 David McLeod Boulevard • Florence, SC 29501
  843-678-9000
  Easily accessible from I-95 and I-20, the Florence Red Roof Inn is within walking distance of many... more...  map

• Sleep Inn
  1833 Florence Park Drive • Florence, SC 29502
  843-662-8558
  Award-winning hotel that offers spacious and comfortable guest rooms with microwaves,... more...  map

• Springhill Suites By Marriott
  2670 Hospitality Boulevard • Florence, SC 29501
  843-317-9050
  SpringHill Suites, Marriott's new moderately priced all-suites hotel, designed for guest who want... more...  map

• Suburban Extended Stay
  1914 West Lucas Street • Florence, SC 29501
  843-665-2575
  The Suburban Extended Stay Florence hotel offers a great location, wonderful amenities and... more...

• Super 8 Motel
  1832 1/2 West Lucas Street • Florence, SC 29501
  843-661-7267
  This convenient property features a long list of modern amenities. Guests enjoy a delicious SuperStart Breakfast each morning and a location right next to restaurants.  map

• Wingate Inn
  2123 West Lucas Street • Florence, SC 29501
  843-629-1111
  You'll find 84 oversized, comfortable guest rooms at this hotel with all rooms including king sized... more...  map

Bed & Breakfast, Cabins & Cottages

• Florence, SC, on VRBO®
  Renting a private vacation home offers the affordability, exceptional value, and personal attention that you deserve. Most private vacation homes offer considerably more space than you will find in the typical hotel room often at a reduced cost. Now, families can vacation together and still have room to breathe. View their list of vacation rentals now...

• Ambrias Garden Manor Bed and Breakfast (circa 1920)
  111 Kuker Street • Florence, SC 29501
  843-661-6060
  Ambrias Garden Manor sits just ten minutes or less from both I-95 and I-20, as well as only one... more...  map

Lodging Guides and Directories

• BedandBreakfast.com
  is a leading directory of bed and breakfasts, inns, and boutique lodgings throughout neighboring South Carolina towns. Shop, compare, and book from their large selection of B&B properties with many exclusive deals offered. Gift certificates are also available. BedandBreakfast.com has nearly 7,000 property listings throughout the United States with 50,000 reviews, 80,000 property photos, and interactive maps.

Condos & Vacation Rentals

• Florence, SC,Vacation Rentals By Owner on VRBO®
  Renting a private vacation home offers the affordability, exceptional value, and personal attention that you deserve. Most private vacation homes offer considerably more space than you will find in the typical hotel room often at a reduced cost. Now, families can vacation together and still have room to breathe. View their list of vacation rentals now...

• HomeAway Vacation Rentals in Florence, SC
  Forget ordinary hotel rooms! Finding the perfect vacation getaway in Florence, SC is easy on HomeAway.com. Choose from 75,000 homes, condos, guesthouses, cottages, and cabins worldwide, and inquire directly with property owners through the site. HomeAway.com vacation rentals offer a unique local experience, often less expensive and more spacious than hotel rooms.

R.V. Parks & Camping

• Florence KOA Campground
  1115 East Campground Road • Florence, SC 29506
  843-665-7007
  Year round quiet and relaxing campground that offers all pull through sites with your choice of... more...  map