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LODGING

Bed & Breakfast, Historic Inns & Hotels

  • Abingdon Manor - A Country Inn
    307 Church Street • Florence, SC 29565
    Latta
    843-752-5090
    This elegant Greek Revival style home has been awarded the Four Diamond award by AAA and features a luxurious two-room suite and four spacious guest rooms, all with private baths and fireplaces. A full breakfast is served each morning and fine dining is available at night. more...  map

  • Ambrias Garden Manor Bed and Breakfast (circa 1920)
    111 Kuker Street • Florence, SC 29501
    843-661-6060
    Ambrias Garden Manor sits just ten minutes or less from both I-95 and I-20, as well as only one hour from Myrtle Beach. It features three newly decorated guest rooms with cable television, alarm clocks, complimentary robes and toiletries. A full southern breakfast is included on your stay. The home is available for special celebrations, small indoor weddings and garden weddings. more...  map

Bed & Breakfast Guides and Directories

  • BedandBreakfast.com
    is a leading directory of bed and breakfasts, inns, and boutique lodgings throughout neighboring South Carolina towns. Shop, compare, and book from their large selection of B&B properties with many exclusive deals offered. Gift certificates are also available. BedandBreakfast.com has nearly 7,000 property listings throughout the United States with 50,000 reviews, 80,000 property photos, and interactive maps.

Condos & Vacation Rentals

  •   Florence, SC,Vacation Rentals By Owner on VRBO® Florence, SC,Vacation Rentals By Owner on VRBO®
    Renting a private vacation home offers the affordability, exceptional value, and personal attention that you deserve. Most private vacation homes offer considerably more space than you will find in the typical hotel room often at a reduced cost. Now, families can vacation together and still have room to breathe. View their list of vacation rentals now...

  •   HomeAway Vacation Rentals in Florence, SC HomeAway Vacation Rentals in Florence, SC
    Forget ordinary hotel rooms! Finding the perfect vacation getaway in Florence, SC is easy on HomeAway.com. Choose from 75,000 homes, condos, guesthouses, cottages, and cabins worldwide, and inquire directly with property owners through the site. HomeAway.com vacation rentals offer a unique local experience, often less expensive and more spacious than hotel rooms.

  •   Rentalo.com Rentalo.com
    saves you time! Click to inquire & compare offers from Vacation Rentals, Hotels, and Bed & Breakfasts in Florence, SC. Find the best deals on short term accommodations using this award-winning, traveler-tested website. Browse our extensive inventory offering leisure and business travelers a wide variety of lodging options; from a budget studio to a luxury villa on a private island, from a small boutique hotel or bed and breakfast to a 5 star resort. Find the perfect place to stay for every occasion including family vacations, romantic getaways, business trips, ski, beach or golf vacations.

  • Florence, SC, Vacation Rentals on Vacation Rentals.com Florence, SC, Vacation Rentals on Vacation Rentals.com
    Are you still making hotel reservations? At VacationRentals.com, customize your next vacation and take advantage of off-season discounts, last minute deals, and freebies! No matter what destination or property type or number of bedrooms you’re looking for, you can find an affordable vacation rental that will suit the needs of you and your fellow travelers. So, what are you waiting for? No matter how tight your budget, you can book your dream vacation on VacationRentals.com today!

Motels/Hotels

  • Best Western Inn
    1808 West Lucas Street • Florence, SC 29501
    843-678-9292
    A variety of amenities are in all of the 74 tastefully decorated guest rooms at this hotel such as hair dryers, coffee makers, microwaves, refrigerators, irons, and ironing boards. An outdoor pool is on site for guests to enjoy and laundry valet service is available. A deluxe continental breakfast is served every morning.  map

  • Comfort Inn
    1916 West Lucas Street • Florence, SC 29501
    843-665-4558
    A variety of spacious guest rooms with an array of great amenities are available at this hotel with all rooms including coffee makers, irons, ironing boards, and hair dryers. On site amenities include a fitness room, outdoor pool, whirlpool, and fax and copy services. A deluxe continental breakfast is served each morning.   map

  • Country Hearth Inn
    831 South Irby Street • Florence, SC 29501
    843-662-9421
    A wide variety of amenities are on site at this elegant hotel including a fitness center, an outdoor swimming pool, a restaurant, cocktail lounge, coffee ship, a bar, maid service, laundry and valet services, and a picnic area. Most of the guest rooms have coffee makers, irons, ironing boards, and refrigerators. A delicious buffet breakfast is served each morning.  map

  • Country Inn & Suites
    1739 Mandeville Road • Florence, SC 29501
    843-317-6616
    Hotel features a continental breakfast, local calls, spacious guest rooms feature desk, coffeemaker, iron/board, hairdryer, and cable tv with HBO. All suites additionally feature microwave and refrigerator. Easy access to I-95.  map

  • Courtyard By Marriott
    2680 Hospitality Boulevard • Florence, SC 29502
    843-662-7066
    Relax in one of the 90 beautifully appointed guest rooms at this hotel with all rooms including coffee makers, large work desks, and data ports. Two room suites and Jacuzzi rooms are also available. On site amenities include an indoor pool, spa, exercise room, a beautiful courtyard with a gazebo, a full service restaurant, laundry valet services, and guest laundry facilities.  map

  • Days Inn
    2111 West Lucas Street • Florence, SC 29501
    843-665-4444
    One king sized bed or two queen sized beds are in all of the 103 spacious guest rooms at this hotel with all rooms also including hair dryers, microwaves, and refrigerators. Some of the rooms have Jacuzzis. On site amenities include an outdoor pool, exercise room, large Jacuzzi, and a sauna. A deluxe continental breakfast is served every morning.  map

  • Days Inn South
    3783 West Palmetto Street • Florence, SC 29501
    843-665-8550
    There are 120 comfortably appointed guest rooms at this hotel that offers microwaves and refrigerators in some of the rooms upon request and irons and ironing boards at the front desk. A full service restaurant that serves delicious country cuisine is on site, as well as an outdoor swimming pool and Jacuzzi. Golf packages are available and guests receive a pass to a nearby tennis court.  map

  • Econo Lodge North
    1811 West Lucas Street • Florence, SC 29501
    843-665-8558
    This hotel offers guests a delicious continental breakfast, ocal calls an indoor heated pool with whirlpool and an exercise room.   map

  • Fairfield Inn Florence
    140 Dunbarton Drive • Florence, SC 29501
    843-669-1666, 800-228-2800
    All of the 135 spacious and comfortable guest rooms at this hotel have work desks with lamps, data ports, irons, and ironing boards. An outdoor pool is on site for guests to enjoy and laundry valet services are available. A continental breakfast is served each morning.  map

  • Guesthouse International
    2001 West Lucas Street • Florence, SC 29503
    843-669-1921
    The GuestHouse International Inn is a beautiful property located on 7 acres of spacious, landscaped grounds. There are 16+ restaurants located right at our exit including Cracker Barrel & Ruby Tuesday. We are only 5 minutes away from the Civic Center and Sports Fields. There are over 18 challenging golf courses within 10 miles. The Hotel is pet friendly.  map

  • Holiday Inn Express Hotel & Suites
    2101 Florence Harlee Boulevard • Florence, SC 29506
    843-629-9779
    This four-story, interior corridor hotel boasts 86 guest rooms & suites. It offers a heated indoor pool, 24-hour business center with high speed Internet access, guest laundry, on-site fitness center and meeting facilities.   map

  • Holiday Inn Hotel & Suites
    1819 West Lucas Street • Florence, SC 29501
    843-665-4555
    Full service hotel that offers 204 luxuriously appointed guest rooms and suites with all rooms including hair dryers, full sized ironing boards and irons, coffee makers, and large work desks. The largest swimming pool in Florence is also located on site at this hotel, as well as a sandy children's play area. Other features of the hotel include a state-of-the-art exercise facility, guest laundry facilities, a putting green, a nightclub, and a full service restaurant that is open for breakfast, lunch, and dinner; room service is available during restaurant hours.  map

  • Howard Johnson Express Inn
    3821 Bancroft Road • Florence, SC 29501
    843-664-9494
    An Award Winning, AAA approved property, this hotel is a perfect stopping point between Florida and New York. They offer high speed internet access, deluxe continental breakfast, a seasonal outdoor pool and more.  map

  • Microtel Inn
    1912 Enterprise Drive • Florence, SC 29502
    843-629-9523
    This property proudly offers a central location near area businesses and attractions. The comfortable accomodations and modern amenities make this a wonderful place for any traveler.  map

  • Ramada Inn
    2038 West Lucas Street • Florence, SC 29501
    Intersection of Interstate Hwy. 95 & U.S. Hwy. 52
    843-669-4241
    A variety of standard amenities are found in the 179 graciously inviting and spacious guest rooms at this hotel that is nestled in the heart of South Carolina and is surrounded by beautiful farms and Spanish Moss. On site amenities include a full service restaurant, a spa, whirlpool, sauna, outdoor pool, exercise room, and a cozy lounge.  map

  • Red Roof Inn
    2690 David McLeod Boulevard • Florence, SC 29501
    843-678-9000
    Easily accessible from I-95 and I-20, the Florence Red Roof Inn is within walking distance of many restaurants, a 13-screen movie theater and the Magnolia Mall with over 70 stores. This Inn is just 10 miles from the Darlington International Raceway and 1 hour from the North Carolina Speedway.  map

  • Sleep Inn
    1833 Florence Park Drive • Florence, SC 29502
    843-662-8558
    Award-winning hotel that offers spacious and comfortable guest rooms with microwaves, refrigerators, and coffee makers in all of the rooms. An outdoor pool is on site for guests to enjoy and fresh hot cookies are served in the lobby each afternoon. A delicious continental breakfast is also served every morning.  map

  • Springhill Suites By Marriott
    2670 Hospitality Boulevard • Florence, SC 29501
    843-317-9050, 888-287-9400
    SpringHill Suites, Marriott's new moderately priced all-suites hotel, designed for guest who want spacious and functional accommodations when on the road even for a few nights at a time. Enjoy a suite, which offers a separate area for eating, sleeping, working and relaing.   map

  • Super 8 Motel
    1832 1/2 West Lucas Street • Florence, SC 29501
    843-661-7267
    This convenient property features a long list of modern amenities. Guests enjoy a delicious SuperStart Breakfast each morning and a location right next to restaurants.  map

  • Wingate Inn
    2123 West Lucas Street • Florence, SC 29501
    843-629-1111
    You'll find 84 oversized, comfortable guest rooms at this hotel with all rooms including king sized beds, irons, and ironing boards; microwaves and refrigerators are also available. A 24 hour business center is on site for guests to use, as well as an exercise room and whirlpool. A deluxe continental breakfast is served each morning. Their customer service is far above expectation!  map

R.V. Parks & Camping

  • Florence KOA Campground
    1115 East Campground Road • Florence, SC 29506
    843-665-7007, 800-562-7807
    Year round quiet and relaxing campground that offers all pull through sites with your choice of shaded or open spaces available. A variety of Kamping Kabins are also on site, as well as an indoor heated pool and an outdoor pool. more...  map

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