Jacob Kelley House Museum (circa 1820) 578 Kelleytown Road, Hartsville, SC 29551, Three Miles West of Hartsville, 888-427-8720, See where the Yankees camped among the Rebels at this house that was taken over by Sherman's Army during the Civil War and is listed on the National Register of Historic Places. The house is filled with period furnishings and offers Civil War reenactments and living history demonstrations on the first Sunday of every month from February through December.

John Lide Hart Cottage 116 East Home Avenue, Hartsville, SC 29550, 843-332-8017, A great example of federal architecture influenced by a vernacular cottage style, this cottage is the oldest building downtown and is the only known structure from John Hart's plantation. The house is completely furnished with period furniture and features an open house on the first Sunday of every month from February to December with costumed docents. 

Hartsville Museum 222 North Fifth Street, Hartsville, SC 29550, Corner of Fifth Street & Home Avenue, 843-383-3005, Located in a historic 1930 post office that is listed on the National Register of Historic Places, this history museum features a permanent collection of Native American artifacts, as well as agricultural implements and silver made in Hartsville. The museum also hosts traveling exhibits and features a lovely gift shop. more... 

Kalmia Gardens of Coker College 1624 West Carolina Avenue, Hartsville, SC 29550, 843-383-8145, Located on the bluffs of Black Creek, these gardens are on the site of the early 19th century plantation of Captain Thomas Edwards Hart for whom Hartsville is named and were developed in the early 1930's by Mrs. David R. Coker. Over 30 acres of trails wind their way through the native and imported plants of these gardens all the way down to Black Creek. more... 

Robinson Visitor Center 3581 West Entrance Road, Hartsville, SC 29550, 843-857-1000, Enjoy an entergy adventure at this center located in the Southeast's first commercial nuclear power plant where visitors can learn the wonders of electricity and energy production through interactive media. A wide variety of interactive exhibits tell the story of nuclear power. 

South Carolina Cotton Trail 214 North Fifth Street, Hartsville, SC 29550, 843-332-6401, This driving tour highlights the cotton industry from farming to ginning and everything in between. Many of the sites along the trail are historical in nature and depict the architecture and way of life during the pioneer days.