LODGING

Bed & Breakfast Guides and Directories

• BedandBreakfast.com
  is a leading directory of bed and breakfasts, inns, and boutique lodgings throughout neighboring South Carolina towns. Shop, compare, and book from their large selection of B&B properties with many exclusive deals offered. Gift certificates are also available. BedandBreakfast.com has nearly 7,000 property listings throughout the United States with 50,000 reviews, 80,000 property photos, and interactive maps.

Condos & Vacation Rentals

• Orangeburg, SC,Vacation Rentals By Owner on VRBO®
  Renting a private vacation home offers the affordability, exceptional value, and personal attention that you deserve. Most private vacation homes offer considerably more space than you will find in the typical hotel room often at a reduced cost. Now, families can vacation together and still have room to breathe. View their list of vacation rentals now...

• HomeAway Vacation Rentals in Orangeburg, SC
  Forget ordinary hotel rooms! Finding the perfect vacation getaway in Orangeburg, SC is easy on HomeAway.com. Choose from 75,000 homes, condos, guesthouses, cottages, and cabins worldwide, and inquire directly with property owners through the site. HomeAway.com vacation rentals offer a unique local experience, often less expensive and more spacious than hotel rooms.

• Rentalo.com
  saves you time! Click to inquire & compare offers from Vacation Rentals, Hotels, and Bed & Breakfasts in Orangeburg, SC. Find the best deals on short term accommodations using this award-winning, traveler-tested website. Browse our extensive inventory offering leisure and business travelers a wide variety of lodging options; from a budget studio to a luxury villa on a private island, from a small boutique hotel or bed and breakfast to a 5 star resort. Find the perfect place to stay for every occasion including family vacations, romantic getaways, business trips, ski, beach or golf vacations.

• Orangeburg, SC, Vacation Rentals on Vacation Rentals.com
  Are you still making hotel reservations? At VacationRentals.com, customize your next vacation and take advantage of off-season discounts, last minute deals, and freebies! No matter what destination or property type or number of bedrooms you’re looking for, you can find an affordable vacation rental that will suit the needs of you and your fellow travelers. So, what are you waiting for? No matter how tight your budget, you can book your dream vacation on VacationRentals.com today!

Motels/Hotels

• Comfort Inn & Suites
  3671 Saint Matthews Road • Orangeburg, SC 29115
  803-531-9200
  The Comfort Inn & Suites is conveniently located less than one mile from the Orangeburg Regional Medical Center. This Orangeburg hotel is close to popular area attractions, including South Carolina State University, Santee State Park, Edisto Memorial Gardens, Claftin College and Lake Marion. Full-service amenities include continental breakfast, local calls, USA Today, outdoor pool and high-speed Internet access.   map

• Days Inn North
  3691 St. Matthews Road • Orangeburg, SC 29115
  803-531-2590
  Relax in one of the 216 beautifully decorated guest rooms at this hotel with all rooms having either one king sized bed or two double beds. There are also four luxurious and spacious suites available. A full service restaurant and an outdoor pool are also on site and a continental breakfast is served every morning. more...  map

• Fairfield Inn
  663 Citadel Road • Orangeburg, SC 29115
  803-533-0014
  A wide variety of thoughtful amenities are in all of the 65 comfortable guest rooms at this room with all rooms including large, well-lit work desks; irons and ironing boards are available upon request. An outdoor pool is on site for guests to enjoy and laundry valet services are available. A continental breakfast is served every morning.

• Hampton Inn
  3583 St. Matthews Road • Orangeburg, SC 29118
  Close to the Regional Medical Center
  803-531-6400
  Beautifully appointed two story hotel that features 69 lovely guest rooms with either king sized or queen sized beds, hair dryers, irons, ironing boards, and coffee makers. On site amenities include complimentary fresh fruit and coffee or tea 24 hours a day in the lobby, fresh baked gourmet cookies Monday through Thursday evenings, and an outdoor seasonal pool. A deluxe continental breakfast is served each morning. more...  map

• Holiday Inn Express Hotel & Suites Orangeburg, Sc
  118 Sleep Inn Road • Orangeburg, SC 29118
  803-539-2900
  Welcome to Orangeburg, the Garden City of South Carolina and home of Edisto Memorial Gardens. Centrally located, Orangeburg is an area of great natural beauty, ideal climate & friendly people, famous for our Southern Charm and Heritage. A golfer's delight, a hunter paradise, a nature lover's dream, just a few reasons to visit Orangeburg County when visiting South Carolina. Our city is perfect for a mini or extended vacation, located just thirty minutes from the Capitol City of Columbia, one ...  map

• Howard Johnson Express Inn
  3608 Old St. Matthews Road • Orangeburg, SC 29115
  803-531-4900
  Conveniently located off I-26, Exit 145A, 35 miles southeast of Columbia and 75 miles northwest of Charleston, SC. This hotel is close to South Carolina State University, Claflin University, O.C. Tech College, Regional Medical Hospital and Downtown Orangeburg restaurants and shopping. They offer high speed internetm a continental breakfast, and an outdoor pool.  map

• Jameson Inn
  2350 Chestnut Street Northeast • Orangeburg, SC 29115
  Off Highway 601 behind Applebess
  803-534-1611, 800-526-3766
  Take advantage of amenities such as work desks, data ports, fitness centers, pools, a deluxe continental breakfast, and newspapers.   map

• Orangeburg - Days Inn South
  Route 2 Box 215 • Orangeburg, SC 29115
  803-534-0500
  Days Inn Conveniently Located Off I-26 Close between Columbia, SC and Charleston, SC. Easy access I-26 Exit 154B(US 301) Quiet and Relaxing, Restaurant on Property. Just the right place to stay after a long day of driving Directly off of the interstate to the property Check in, have Dinner, relax for a good nights sleep Up in the morning, have Breakfast, in our Restaurant Check-out and back on the I-26 to finish your trip Charleston,South Carolina-55 miles Savannah, Georgia is only 110 miles ...  map

• Quality Inn & Suites
  1415 John C. Calhoun Drive • Orangeburg, SC 29115
  803-531-4600
  The only full service hotel in Orangeburg, this hotel offers 141 beautifully appointed guest rooms and suites with all rooms including coffee makers, hair dryers, irons, and ironing boards; microwaves and refrigerators are available. Oversized family rooms with sleeper sofas, whirlpool rooms, and honeymoon suites with king sized beds are also available. On site amenities include a full service restaurant, a lounge, a fitness facility, and a large heated outdoor pool.  map

• Sleep Inn
  3689 St. Matthews Road • Orangeburg, SC 29115
  803-531-7200
  Sleep Inn offers interior Corridor rooms, PC hookups, 25in TV, and desk in all rooms. Guest laundry and elevator are also on property.  map

• Super 8 Motel
  610 John Calhoun Drive • Orangeburg, SC 29115
  803-531-1921
  The Super 8 of Orangeburg offers guests a delicious continental breakfast. It is located within walking distance from the South Carolina Claflin University. Large and spacious guest rooms with a pool for all to enjoy. Guests enjoy local newspaper daily, 24 hour front desk, a fitness center, spa and golf nearby.  map