Santee, SC,Vacation Rentals By Owner on VRBO® Renting a private vacation home offers the affordability, exceptional value, and personal attention that you deserve. Most private vacation homes offer considerably more space than you will find in the typical hotel room often at a reduced cost. Now, families can vacation together and still have room to breathe. View their list of vacation rentals now...

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Value Vacation Rentals Value Vacation Rentals is a great way to find the perfect rental home for your next vacation. You will find everything from luxury beachfront homes to comfortable villas or condos. Also, since they put you directly in contact with the property owner or manager, you will get the best value available for your vacation rental. So, plan your next vacation today. more...

Ashley Inn, The 9112 Old Highway #6, Santee, SC 29142, 803-854-3870, Your choice of one queen sized bed or two double beds is available at this Howard Johnson family inn that offers fresh and comfortable ground floor rooms with thoughtful amenities to make you feel right at home. An outdoor pool and a beautiful garden patio are on site for guests to enjoy and a deluxe continental breakfast is served every morning. Golf and fishing packages are a specialty of this hotel.

Baymont Inn & Suites 249 Britain Street, Santee, SC 29142, 803-854-3221, Welcome to the Baymont Inn & Suites Santee. They are conveniently located to the relaxing recreational attractions of Santee. Lake Marion Golf Course is 3/4 of a mile from the hotel. Rent a boat and fish on Lake Marion - 3 miles away. And take the whole family to the Santee State Park or the Santee Wildlife Refuge. If shopping is a must, the Santee Outlets are within 1 mile. While staying with Baymont Inn & Suites, you will find the rooms are well equipped for all your needs. 

Best Western Inn Interstate 95, Exit 98, 803-854-2141, 800-528-1234, Beautiful Charleston style inn that overlooks the scenic Lake Marion Golf Course and offers 107 distinctively decorated guest rooms with coffee makers, irons, ironing boards, hair dryers, microwaves, and refrigerators. A seasonal heated Grecian outdoor pool is on site for guests to enjoy, as well as a full service restaurant. A continental breakfast is served each morning. more...

Best Western Santee Interstate 95, Santee, SC 29142, 803-854-3089, An upscale property with well appointed rooms. We have an excellent new restaurant, all rooms are ground floor, and some are equipped with whirlpool baths. In the morning, you may choose to relax in our seasonal heated outdoor pool or spend the day at the golf course, fishing, shopping or enjoy the National Wildlife Refuge. We have a privileged location just off Interstate 95 for easy on and off highway access. We look forward to your stay with us. 

Clark's Inn 114 Bradford Boulevard, Santee, SC 29142, 803-854-2141, All of the comforts of home are provided at this lovely inn that is decorated in a traditional bed and breakfast style and offers spacious king deluxe guest rooms and luxurious suites. A full service restaurant is on site, as well as an outdoor garden pool and guest laundry facilities.

Comfort Inn 249 Britain Street, Santee, SC 29142, One Mile from Lake Marion, 803-854-3221, There are 60 spacious guest rooms, including two elegantly appointed suites with whirlpool tubs and microfridges, available at this friendly hotel with all of the rooms including large workspaces, irons, ironing boards, hair dryers, and coffee makers. An outdoor pool is on site for guests to enjoy and a deluxe continental breakfast is served every morning. Cookies, tea, and coffee are available every evening.

Country Inn And Suites 221 Britain Street, Santee, SC 29142, 803-854-4104, Ideally located in the heart of Santee golf country in South Carolina. Three courses are within one mile and ten courses are within 20 minutes. Hotel has putting green. All units feature wireless high speed Internet access, coffeemaker and iron/board. Hotel offers outdoor parking. 

Days Inn 9074 Old Highway #6, Santee, SC 29142, 803-854-2175, All of the 119 well appointed guest rooms at this lovely hotel have coffee makers, microwaves, and refrigerators. Guest laundry facilities are on site and laundry valet services are available. A delicious continental breakfast is served every morning. more...

Hampton Inn 9060 Old #6 Highway, Santee, SC 29142, 803-854-2444, Beautiful hotel that offers 81 comfortably appointed guest rooms with either one king sized or two queen sized beds, coffee makers, irons, ironing boards, hair dryers, microwaves, and refrigerators. On site amenities include an outdoor pool, indoor whirlpool, exercise room, a 24 hour business center, guest laundry facilities, and boat parking with hookups. A deluxe continental breakfast is served each morning and fresh baked cookies are available each evening. more...

Holiday Inn 139 Bradford Boulevard, Santee, SC 29142, 803-854-9800, Surrounded by history and beauty, the Holiday Inn Hotel Santee, provides you with Southern charm in a contemporary facility, conveniently located in the heart of Santee Cooper Country, off I-95, half way between Miami & New York. 

Quality Inn & Suites 8929 Bas Drive, Santee, SC 29142, 803-854-2121, Located within walking distance to restaurants, Quality Inn offers executive rooms and suites available. Each room features a Quality Sleeper by Serta Bedding. All rooms have in-room coffee. Amenities include an exercise room onsite, a beautiful courtyard and a public hot tub. 

Ramada Inn 123 Mall Drive, Santee, SC 29142, 803-854-2191, All of the professionally decorated guest rooms at this hotel have numerous amenities such as extra length bedding. Guests of this hotel can enjoy the outdoor pool or live entertainment Thursday through Saturday in the onsite lounge. A full service restaurant is also on site that serves breakfast and dinner daily.  

Super 8 Motel 9125 Old Highway 6, Santee, SC 29142, 803-854-3456, 41 nicely appointed rooms, all ground floor. Your home base for exploring the Santee area. Easy access to I-95, exit 98. All double rooms boast 2 queen size beds. Ask about their numerous Golf Packages, 12 golf courses within 20 minutes or closer, rooms with whirlpool tubs available, Super Start breakfast, delicious made to order Belgian waffles, ample large vehicle parking, with outdoor plugs. 

Travelodge 9091 Old Highway 6, Santee, SC 29142, 803-854-3122, The Travelodge Santee is located in the heart of Santee's golf, fishing and nature parks, and puts you minutes away from South Carolina's celebrated sports and recreational destinations. Walking distance to restaurants and shopping. All of our rooms have microfridges and High Speed Wireless Internet. Complimentary make your own waffles breakfast. Pet-Friendly: $5.00 charge per day per pet. Golf packages available year round.