Lodging in Orangeburg, South Carolina

Hotels, Lodges, Extended Stay

Comfort Inn & Suites 803-531-9200
3671 Saint Matthews Road, Orangeburg, SC 29115
The Comfort Inn & Suites is conveniently located less than one mile from the Orangeburg Regional Medical Center. This Orangeburg hotel is close to popular area... more info map
Days Inn North 803-534-0500
3402 Five Chop Road, Orangeburg, SC 29115
Relax in one of the 216 beautifully decorated guest rooms at this hotel with all rooms having either one king sized bed or two double beds. There are also four luxurious and spacious suites available. A full service restaurant and an outdoor pool are also on site and a continental breakfast is served every morning. map
Days Inn Orangeburg South 803-534-0500
3402 Five Chop Road, Orangeburg, SC 29115
Lovely hotel that features a full service restaurant and lounge on site plus offers 100 tastefully appointed guest rooms with all of the standard amenities to make you feel right at home. An outdoor pool is on site to help guests relax and meeting and banquet facilities are available. map
Fairfield Inn 803-533-0014
663 Citadel Road, Orangeburg, SC 29115
A wide variety of thoughtful amenities are in all of the 65 comfortable guest rooms at this room with all rooms including large, well-lit work desks; irons and ironing... more info
Hampton Inn 803-531-6400
3583 St. Matthews Road, Orangeburg, SC 29118
Close to the Regional Medical Center
Beautifully appointed two story hotel that features 69 lovely guest rooms with either king sized or queen sized beds, hair dryers, irons, ironing boards, and coffee... more info map
Holiday Inn Express Hotel & Suites Orangeburg, Sc 803-539-2900
118 Sleep Inn Road, Orangeburg, SC 29118
Welcome to Orangeburg, the Garden City of South Carolina and home of Edisto Memorial Gardens. Centrally located, Orangeburg is an area of great natural beauty, ideal... more info map
Howard Johnson Express Inn 803-531-4900
3608 Old St. Matthews Road, Orangeburg, SC 29115
Conveniently located off I-26, Exit 145A, 35 miles southeast of Columbia and 75 miles northwest of Charleston, SC. This hotel is close to South Carolina State... more info map
Jameson Inn 803-534-1611
2350 Chestnut Street Northeast, Orangeburg, SC 29115
Off Highway 601 behind Applebess
Take advantage of amenities such as work desks, data ports, fitness centers, pools, a deluxe continental breakfast, and newspapers. more info map
Quality Inn & Suites 803-531-4600
1415 John C. Calhoun Drive, Orangeburg, SC 29115
The only full service hotel in Orangeburg, this hotel offers 141 beautifully appointed guest rooms and suites with all rooms including coffee makers, hair dryers, irons,... more info map
Sleep Inn 803-531-7200
3689 St. Matthews Road, Orangeburg, SC 29115
Sleep Inn offers interior Corridor rooms, PC hookups, 25in TV, and desk in all rooms. Guest laundry and elevator are also on property. more info map
Southern Lodge 803-531-7333
3616 St. Matthews Road (Highway 601), Orangeburg, SC 29118
An affordable Orangeburg hotel. more info
Super 8 Motel 803-531-1921
610 John Calhoun Drive, Orangeburg, SC 29115
The Super 8 of Orangeburg offers guests a delicious continental breakfast. It is located within walking distance from the South Carolina Claflin University. Large and... more info map

Bed & Breakfast, Cabins & Cottages

Thee Matriarch Bed & Breakfast 803-937-4271
1170 Fischer Street, Orangeburg, SC 29115
Located in Historic Downtown Orangeburg
A spacious home-style boutique inn and rental facility, Thee Matriarch Bed & Breakfast, Meeting and Special Events Venue offers four guest accommodations, tantalizing... more info map

Lodging Guides and Directories

Condos & Vacation Rentals

Print - Lodging